Gluten-free, una moda?
Less than 1 percent of Americans have the disorder that requires a gluten-free diet, yet nearly one in three now eschews gluten, according to trend watchers NPD Group, influenced by bestselling anti-gluten books and celebrity endorsements. The U.S. market for gluten-free foods will climb from $4.2 billion in 2012 to $6.6 billion by 2017, according to researcher Packaged Facts, as bread bakers, craft-beer makers and eateries from Hooters to Michelin-starred Hakkasan embrace the trend.
“Consumers, rightly or wrongly, have made a connection between gluten-free and healthy,” said Nicholas Fereday, an analyst at Rabobank. “Grain companies are hoping this trend crashes and burns sooner rather than later. But any trend is a marketing opportunity.”
Study: they fed a high-fat diet containing 4.5% gluten to a control group of C57BL/6 mice, and a gluten-free diet to another group of C57BL/6 mice. The team measured body weight and adiposity gains,leukocyte rolling and adhesion, macrophageinfiltration and cytokine production in adipose tissue. They also measured blood lipidprofiles, glycaemia, insulin resistance and adipokines, and determined expression of the PPAR-α and γ, lipoprotein lipase (LPL), hormone sensitive lipase (HSL), carnitine palmitoyl acyltransferase-1 (CPT-1), insulinreceptor, GLUT-4 and adipokines in epidydimal fat.
The gluten-free mice had less body weight gain and adiposity, with no changes in food intake or lipid excretion. These results are associated with up-regulation of PPAR-α, LPL, HSL and CPT-1, which are related to lipolysis and fatty acid oxidation.
Gluten-free mice also showed improved glucose homeostasis and pro-inflammatory profile-related over-expression of PPAR-γ. Moreover, intravital microscopy showed a lower number of adhered cells in the adipose tissue microvasculature. The overexpression of PPAR-γ is related to the increase of adiponectin and GLUT-4.
The study data support the beneficial effects of gluten-free diets in reducing adiposity gain, inflammation and insulin resistance. The data suggests that a gluten-free diet should be tested as a new dietary approach to preventing obesity and metabolic disorders.
La incidencia de problemas digestivos en USA es muy alta, y las dietas Paleo y Sin Gluten cada vez mas de moda…