https://www.technologyreview.com/s/5346 ... ging-pill/
The problem, Guarente says, is that it’s nearly impossible to prove, in any reasonable time frame, that drugs that extend the lifespan of animals can do the same in people; such an experiment could take decades. That’s why Guarente says he decided to take the unconventional route of packaging cutting-edge lab research as so-called nutraceuticals, which don’t require clinical trials or approval by the FDA.
This means there’s no guarantee that Elysium’s first product, a blue pill called Basis that is going on sale this week, will actually keep you young. The product contains a chemical precursor to nicotinamide adenine dinucleotide, or NAD, a compound that cells use to carry out metabolic reactions like releasing energy from glucose. The compound is believed cause some effects similar to a diet that is severely short on calories—a proven way to make a mouse live longer.
Elysium’s approach to the anti-aging market represents a change of strategy for Guarente. He was previously involved with Sirtris Pharmaceuticals, a high-profile biotechnology startup that studied resveratrol, an anti-aging compound found in red wine that it hoped would help patients with diabetes. That company was bought by drug giant GlaxoSmithKline, but early trials failed to pan out.
http://nymag.com/scienceofus/2016/08/is ... youth.html
Elysium Health is an anti-aging supplement manufacturer which recently released a pill calledBASIS. BASIS claims to turn back the signs of aging by literally repairing your DNA.
Normally, this is the part where people click away, thinking Elysium Health is another anti-aging supplement scam.
But it’s not: Elysium Health is a legitimate company founded by one of the world’s leading anti-aging researchers. Oh, and he’s being advised by five Nobel Prize winners.
Those two gym buddies – cofounders Eric Marcotulli and Dan Alminana – knew that they didn’t have the scientific background to build such a company. They were tech investors, not biologists. So they started calling anti-aging researchers across the United States.
That’s when MIT biologist Leonard Guarentepicked up the phone and expressed interest. And he wasn’t alone: five Nobel Prize winners also jumped on as advisors along with over 20 other top researchers in their fields.
BASIS contains two building blocks for NAD: it gives your body the tools it needs to produce NAD on its own. Yes, there are just two ingredients needed to stimulate NAD levels in the body. Those ingredients are:
— Nicotinamide Riboside (250mg)
— Pterostilbene (50mg)
These two ingredients are absorbed by the body and ultimately transform into NAD. Then, that NAD goes to work performing critical tasks throughout the body, including:
— DNA repair
— Energy production
— Cellular detoxification
— Protein function
All of these functions lead to powerful anti-aging, health-boosting benefits.
Elysium Health cofounder Marcotulli said, “We have no interest in being an anti-aging company and extending lifespan. For us this is about increasing healthspan, not lifespan.”
Why? The founders wanted to avoid the “charlatan feel” of the countless other anti-aging supplements on the market today. Too many low-quality manufacturers claim they’ve found the secret to turning back the clock and reverse the effects of aging – despite having no scientific evidence to back it up.
Nota: Leonard Guarante takes 250 mg of resveratrol along with Basis