Inmortalidad

Reglas del Foro
Por favor procura que tus comentarios estén relacionados con la entrada y no pongas enlaces no relevantes. Intenta también respetar a los demás, los comentarios promocionales, ofensivos o ilegales serán editados y borrados. La información o los datos presentes en la web se suministran únicamente a título informativo. Por tanto, corresponde a cada usuario verificar esta información antes de tomar ninguna decisión basada en ella. El usuario es el único responsable del uso que haga de los datos y la información provenientes de la web.
Avatar de Usuario
Dalamar
Site Admin
Mensajes: 8368
Registrado: 09 May 2012 01:38
Ubicación: En Communera! Creando comunidades!
Contactar:

Re: Inmortalidad

Mensajepor Dalamar » 18 Feb 2017 08:19

Ver: http://www.longevityreporter.org/blog/2 ... -sirtuin-6

In a new paper published in the prestigious journal Angewandte Chemie International Edition researchers succeeded in developing the first class of synthetic molecules that activates the SIRT-6 protein. While it was previously found that fatty acids could weakly activate SIRT-6, no SIRT-6 activators were known that exhibited ‘drug-like properties’. This discovery could potentially lead to a new class of anti-aging drugs.
Adjuntos
SIRT6.PNG
¿Te ha gustado este hilo? Retweetealo para que se sume mas gente a la conversacion!

Avatar de Usuario
Dalamar
Site Admin
Mensajes: 8368
Registrado: 09 May 2012 01:38
Ubicación: En Communera! Creando comunidades!
Contactar:

Re: Inmortalidad

Mensajepor Dalamar » 26 Mar 2017 17:43

Fuente: http://www.sciencealert.com/scientists- ... ng-in-mice

Researchers have identified a cellular mechanism that allows them to reverse ageing in mouse DNA and protect it from future damage.

They've shown that by giving a particular compound to older mice, they can activate the DNA repair process and not only protect against future damage, but repair the existing effects of ageing. And they're ready to start testing in humans within six months.

"The cells of the old mice were indistinguishable from the young mice, after just one week of treatment," said lead researcher David Sinclair from the University of New South Wales (UNSW) in Australia and the Harvard Medical School in Boston.

"This is the closest we are to a safe and effective anti-ageing drug that's perhaps only three to five years away from being on the market if the trials go well."

Sinclair and his team made headlines back in 2013 when they found that the cells of younger mice contained more of a compound called nicotinaminde adenine dinucleotide, or NAD+, than their older counterparts.

Not only that, but when they gave the older mice more NAD+, they started to look younger, too.

It was a big deal at the time, but one of the tricky things about medicine is that in order to show that something could work as a potential treatment, you need to first understand how it's acting in the body.

And although the researchers knew NAD+ was having an impressive effect, they couldn't say for sure how it was doing it.

They now plan to trial a similar drug in humans before the end of the year - and not just for anti-ageing purposes, but also to protect against DNA damage of any kind.

In fact, the team is collaborating with NASA to see if NMN could help protect its astronauts against harsh space radiation on their four-year journey to Mars, during which it's predicted that 5 percent of the astronauts' cells would die, and their chances of cancer would approach 100 percent.
¿Te ha gustado este hilo? Retweetealo para que se sume mas gente a la conversacion!

Avatar de Usuario
Dalamar
Site Admin
Mensajes: 8368
Registrado: 09 May 2012 01:38
Ubicación: En Communera! Creando comunidades!
Contactar:

Re: Inmortalidad

Mensajepor Dalamar » 28 Mar 2017 17:51

Novartis’s study on everolimus, which looked at whether the immune system of elderly people could be made to act younger, has been called the “first human aging trial.”

Last week a Boston company, PureTech Health, said it was licensing two drug molecules, and the right to use them against aging-related disease, from Novartis and making the research the basis of a startup company, resTORbio. The company says it will further test whether such drugs can rejuvenate aged immune cells.

The drug Novartis tested is a derivative of rapamycin, a compound first discovered oozing from a bacterium native to Easter Island, or Rapa Nui, and named after it. Thanks to its broad effects on the immune system, rapamycin has already been used in transplant medicine as an immune suppressant and a version is sold by Novartis as the anticancer prescription Afinitor.

How much should society invest in trying to halt aging?
Tell us what you think.
What’s even more interesting about rapamycin, however, is its reputation as the most consistent way to postpone death, at least in laboratory species. It lengthens the lives of flies, worms, and rodents, too. Feed the compound to mice and they live 25 percent longer, on average.
¿Te ha gustado este hilo? Retweetealo para que se sume mas gente a la conversacion!

Avatar de Usuario
alejperez
Especulador Novato
Mensajes: 123
Registrado: 29 May 2012 20:55
Contactar:

Re: Inmortalidad

Mensajepor alejperez » 06 Abr 2017 13:57

He encontrado por casualidad este blog,

https://westhunt.wordpress.com/

La verdad es que estoy empezando a leerlo, pero parece tratar del tema de la extensión de la vida, saludo y similares, mezclado con algo de historia, lingüística, genética.., bueno, estoy empezando a mirarlo, pero parece interesante.

Avatar de Usuario
Dalamar
Site Admin
Mensajes: 8368
Registrado: 09 May 2012 01:38
Ubicación: En Communera! Creando comunidades!
Contactar:

Re: Inmortalidad

Mensajepor Dalamar » 06 Abr 2017 16:41

Tiene muy buena pinta...
¿Te ha gustado este hilo? Retweetealo para que se sume mas gente a la conversacion!

Jjt37
Iniciandose
Mensajes: 19
Registrado: 29 Mar 2015 23:40

Re: Inmortalidad

Mensajepor Jjt37 » 07 Abr 2017 10:23

No me ha dado tiempo de leerlo,pero una fundación de BBVA ha sacado un ebook que habla un poco de todo,extensión de vida,fintech,robótica...colabora Aubrey de Grey y...Fco Gonzalez :lol:

https://www.bbvaopenmind.com/libro/el-proximo-paso-la-vida-exponencial/

Avatar de Usuario
Dalamar
Site Admin
Mensajes: 8368
Registrado: 09 May 2012 01:38
Ubicación: En Communera! Creando comunidades!
Contactar:

Re: Inmortalidad

Mensajepor Dalamar » 24 Abr 2017 04:33

Five years from now, it will be possible to fly to an overseas clinic and undergo a treatment that will clear out between a quarter and half of the senescent cells in your body. That will to some degree damp down fibrosis, restore tissue elasticity, reduce inflammation, reduce calcification of blood vessels, and in addition improve many other measures of health that are impacted by the normal progression of aging. In short you will walk away a little rejuvenated, literally: one of the root causes of aging will be turned back for some years, perhaps decades, however long it takes for the removed senescent cells to emerge once again. Given the present cost of senolytic drug candidates, varying widely per dose depending on whether or not they are at present mass manufactured, I think that the likely initial cost of treatment five years from now will be somewhere in the 5,000 to 25,000 range. Higher would seem unlikely, given that this is a competitive area of development already, and lower will probably have to wait for bigger players to enter the game in regulated markets. That cost will then fall as availability spreads.

Senolytics are just the start. Five years to a decade after the first candidate therapy for breaking glucosepane cross-links in humans, that treatment will also be available to anyone with the necessary funds put aside. It will also turn back the clock, removing some portion of one of the root causes of aging. Tissue elasticity will be restored, hypertension controlled as arteries become more flexible, and scores of other consequences of cross-linking reduced in their impact. That first therapy could emerge in the laboratories this year or at any time thereafter; a number of groups are working on it. There are a range of other rejuvenation treatments and compensatory therapies at similar points, on the verge in one way or another. Gene therapies to boost muscle generation, or dramatically reduce blood cholesterol. Approaches to clear harmful amyloids from old tissue. The next twenty years will bring numerous opportunities to benefit for anyone willing organize their own treatments via medical tourism, and who happens to know enough about the field to pick out the metal from the dross.
¿Te ha gustado este hilo? Retweetealo para que se sume mas gente a la conversacion!

Avatar de Usuario
Dalamar
Site Admin
Mensajes: 8368
Registrado: 09 May 2012 01:38
Ubicación: En Communera! Creando comunidades!
Contactar:

Re: Inmortalidad

Mensajepor Dalamar » 29 Abr 2017 05:44

Ya se ha transplantado una cabeza con exito en monos, en humanos se va a realizar el transplante en 10 meses... Se calcula que en 3 años se prodra realizar un transplante de cerebro, esto puede tener implicaciones serias!

Imagina, una persona de edad avanzada, sin escrupulos y con mucho dinero que decide mover su cerebro a un cuerpo joven, seguramente aunque esto no rejuvenezca su cerebro, le permita vivir varias decadas extra.

Por otro lado en algun momento puede que con celulas madre podamos construir cuerpos de recambio y transplantar nuestros cerebros!
¿Te ha gustado este hilo? Retweetealo para que se sume mas gente a la conversacion!


Volver a “Off-Topic”

Ingresar