La cura de la enfermedad celiaca

Problemas con lo que comemos, alimentos que no nos sientan bien y que aunque no lo notemos causan una reaccion autoinmune en el organismo que nos hace sentir mal y tener diversos sintomas que quiza no identifiquemos.
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Dalamar
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La cura de la enfermedad celiaca

Mensajepor Dalamar » 24 Dic 2013 11:44

The University of Chicago’s Celiac Research Center, among others, is at the forefront of research and education. Their annually published Research Summary Report outlines exciting discoveries which most certainly will have a great impact on the diagnosis and treatment of Celiac Disease.

“There is today strong evidence that a cure that would allow to freely eat gluten is possible. However, it is further down the road and may take 10-20 years to be available to patients with celiac disease” Dr. Dr. Bana Jabri, professor at University of Chicago and one of the world’s leading researchers of celiac disease (as noted in Media Planet article (6.2013).

http://www.cureceliacdisease.org/wp-con ... t_2013.pdf
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Re: La cura de la enfermedad celiaca

Mensajepor Dalamar » 23 Dic 2014 10:22

Abhilok Garg, Ph.D., an immunology analyst with research and consulting firm GlobalData, is projecting sales such drugs in the US and five major European markets Germany, France, Spain, Italy and the UK, to reach approximately $551.1 million by 2023.

The launches of Alba/Teva’s larazotide acetate, Alvine/AbbVie’s latiglutenase, and BioLineRX’s BL-7010 portend a new world of therapies for the estimated 600,000 diagnosed celiac patients in these countries.

With early trials looking promising and no obvious problems on the horizon, analysts expect larazotide acetate to enter the US and 5EU markets in Q1 2018 and Q1 2019, respectively, followed by latiglutenase in Q1 2019 and Q1 2020.

Latiglutenase is currently being developed as a chronic drug treatment, GlobalData’s interviews with KOLs have indicated that clinical experience with this drug could dictate the way it is prescribed to patients, and that it may in some cases be used as an “on demand” treatment,” says Dr. Garg.

Larazotide acetate works by modulating tight junctions (TJs) in the small bowel epithelium, and has tried to maximize recent research showing that people with celiac disease do have altered intracellular spaces and TJ structures in the lower esophagus.

BL-7010 works by sequesteringgliadins, effectively masking them from enzymatic degradation and preventing the formation of immunogenic peptides that trigger an adverse immune reaction when people with celiac disease consume wheat. BL-7010 has cleared early trial hurdles and been found to be safe and well tolerated in both single and repeated-dose administrations.
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