Alzheimer

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Alzheimer

Mensajepor Dalamar » 17 Nov 2014 19:31

Bueno saberlo con antelacion!

Alzheimer’s Test Detects Disease Decade Ahead of Onset
Nov 17, 2014 http://www.bloomberg.com/news/2014-11-1 ... onset.html

A new blood test for Alzheimer’s appears to detect the disease as many as 10 years before clinical diagnosis is possible -- far sooner than other tests in development.

The test, described publicly for the first time yesterday, could soon be used to identify and treat patients with Alzheimer’s earlier in their disease progression. Those people could participate in clinical trials to help find new treatments. Already, the test distinguishes between patients and healthy elderly with 100 percent accuracy.


Two other potential Alzheimer’s blood tests were announced earlier this year. One measures 10 fats in the bloodstream that appear to predict dementia with 90 percent accuracy within three years of its onset. Another uses 10 proteins in the blood to predict onset with 87 percent accuracy within a year.

At the National Institute on Aging, Kapogiannis and his team identified a single protein in the brain involved in insulin signaling, called IRS-1, that appears to be defective in Alzheimer’s patients.
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Re: Alzheimer

Mensajepor Dalamar » 25 Nov 2014 04:20

Over five million Americans have Alzheimer's disease today. According to the CDC, a person's chances of developing age-related dementia double every 5 years after age 65.

Alzheimer's-related mortality has increased 68% since 2000. Heart disease deaths are down 16%. Stroke deaths are down 23%.

These statistics suggest that the less likely one is to succumb to traditional causes of mortality, the more likely they are to develop Alzheimer's.

Currently, there's a $67 billion yearly unmet need in Alzheimer's drug treatment and a $220+ billion care for the aging market yearning for a new Alzheimer's treatment with promise.
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Re: Alzheimer

Mensajepor Dalamar » 15 Dic 2014 22:40

Exercise Counteracts Genetic Risk for Alzheimer’s

Scientific American reports that new evidence suggests the same gene that makes one more susceptible to cognitive decline dementias later in life can be modulated to provide more protection against Alzheimer’s via exercise. Scientists have known for some time that those with the APOE e4 gene have an elevated Alzheimer’s risk. But APOE e4 also responds to exercise, and those in middle age can derive protective benefits against later mental decline. Though some conflicting evidence clouds APOE e4’s direct role in Alzheimer’s, the more active one is, research suggests, the better the brain fares later in life.
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Re: Alzheimer

Mensajepor Dalamar » 01 Sep 2016 19:22

A new antibody treatment designed to tackle Alzheimer's has been shown in a pilot study to effectively break down the plaques in the brain thought to cause the disease.
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Re: Alzheimer

Mensajepor Dalamar » 21 Jun 2017 20:17

Extra virgin olive oil staves off Alzheimer's, preserves memory, new study shows

Temple University research shows extra-virgin olive oil protects against memory loss, preserves the ability to learn and reduces conditions associated with Alzheimer's disease.
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Re: Alzheimer

Mensajepor Dalamar » 19 Ago 2017 19:12

The MIND diet encourages high consumption of 10 “brain-healthy” food groups such as green leafy vegetables, other vegetables, nuts, berries, and fish. It limited (note: not banned) consumption of unhealthy food groups like red meats, butter and stick margarine, cheese, sweets, and processed foods. The findings, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, revealed that older adults who adhered strictly to the MIND diet faced a 53% lower risk of Alzheimer’s, and those who followed it moderately saw their risk lower by 35%.
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Re: Alzheimer

Mensajepor Dalamar » 18 Sep 2017 05:25

Inteligencia artificial para detectar Alzheimer con una decada de antelacion:

Various researchers around the globe are developing ways to detect Alzheimer's as early as possible. After all, early detection gives people the power seek treatment that can slow down the condition's effects, as well as enough time to get their legal and financial affairs in order. Some decided to focus on blood and cerebrospinal fluid tests, while others are developing gadgets that can look for early signs. A team of researchers from the University of Bari in Italy, however, believe the answer lies in artificial intelligence. They developed an algorithm that can spot tiny structural changes in the brain caused by the disease a decade before symptoms even appear.

They trained their AI by feeding it 67 MRI scans -- 38 from Alzheimer's patients and 29 from healthy controls. The researchers divided the scans into small regions and had their AI analyze the neuronal connectivity between. After training was done, they tested the algorithm by having it process brain scans from 148 subjects. Out of the total number, 48 were scans of people with the disease, while 48 were scans of people who suffered from mild cognitive impairment and eventually developed full-blown Alzheimer's.

The AI was able to diagnose Alzheimer's 86 percent of the time. More importantly, it was able to detect mild cognitive impairment 84 percent of the time, making it a potentially effective tool for early diagnosis. Unfortunately, the researchers were limited to the scans in USC LA's Alzheimer's Disease Neuroimaging Initiative database. With more samples and further development, though, the AI could become more accurate until it's reliable enough to be used as a non-invasive early detection system.
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