Why Sleeping prevents cancer via downregulating Myc
Dr. Watson then explains a fascinating finding of how circadian rhythms affect Myc levels. Using RNAi screens of cancer, a specific gene called CSNKe was discovered, which led to the discovery that the circadian clock protein PER2 can act as a tumor suppressor. Specifically, when the PER2 protein is phosphorylated by CSNKe, it undergoes proteasomal degradation. By blocking CSNKe, PER2 selectively binds to DNA promoter sites and turns off many genes, including the MYC gene. Cancer biologist are now starting to develop CSNKe inhibitors, which are a new, promising way of turning off Myc. However, you can do this every night with a good nights sleep as well. This is one explanation of why sleep is so important for cancer prevention.
A new device, worn like regular spectacles, is helping shift workers and jet-lagged travellers get much-needed shuteye. Called Re-Timer, the glasses improve sleep by helping reset the user's sleep rhythms.
Napping Improves Memory Five-Fold And Enhances Learning Success, Study ...
Researchers at Saarland University in Germany have found in a recent study that napping for just 45 to 60 minutes can improve memory five-fold while simultaneously improving learning success.
“Hidden caves” that open up in the brain may help explain sleep’s amazing restorative powers.
A new study published in the prestigious journal, Science, has found that the brain may wash away toxins built up over the day during sleep.
The research discovered “hidden caves” inside the brain, which open up during sleep, allowing cerebrospinal fluid (CSF) to flush out potential neurotoxins, like β-amyloid, which has been associated with Alzheimer’s disease.
Worrisome news for people who toss and turn all night: Insomnia appears to be linked to a heightened risk for heart attack or stroke, a research review from China suggests.
"We found that difficulty initiating sleep, difficulty maintaining sleep, or non-restorative sleep were associated with 27 percent, 11 percent, and 18 percent higher risks of cardiovascular and stroke events, respectively," said study co-author Qiao He.
For this report, the investigators looked at 15 studies that enlisted nearly 161,000 participants in all. The studies variously explored potential links between insomnia and a range of heart disease concerns, including heart attack, stroke and heart failure.
Sleep deprivation can cause brain to start 'eating' itself
A lack of sleep can cause parts of the brain's synapses to be 'eaten' by other brain cells, according to a new study by researchers at the Marche Polytechnic University in Italy.