Inflamación

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Dalamar
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Inflamación

Mensajepor Dalamar » 04 Ene 2014 11:11

La inflamación es un proceso natural para combatir agentes externos perjudiciales, pero tambien forma parte de enfermedades cronicas, cancer etc... La actual dieta contiene un monton de alimentos pro-inflamatorios, por ello en este hilo vamos a analizar que es pro-inflamatorio y que es anti-inflamatorio:

Inflammation results from the innate biological response of vascular tissues to harmful agents, such as pathogens or irritants. It is an attempt by the organism to remove the injurious stimuli, protect the surrounding tissue, and initiate the healing process. However, unabated chronic inflammation also contributes to a host of diseases, such as atherosclerosis, asthma, and rheumatoid arthritis. Elevated levels of oxidative stress play an important role in chronic inflammation. Oxidative stress-associated inflammation is thought to provoke early vascular events in atherogenesis, including the upregulation of vascular adhesion molecules and matrix metalloproteinase activity. These events require the activation of NF-kappaB, a transcription factor that induces expression of many genes involved in inflammation and endothelial cell migration. Given the oxidative nature of inflammation, therapeutic strategies aimed at mitigating oxidant production and oxidative damage have been investigated for decades in various models of inflammation.


Vamos a buscar anti-inflamatorios diferentes a los clasicos NSAID (Non-steroidal anti-inflammatory drug) que habitualmente tienen efectos perjudiciales en el estomago y son causantes de ulceras, gastritis etc...

Como potentes anti-inflamtorios vamos a mencionar (para empezar):
- Turmeric/Curcumin: alimentos-saludables-f112/turmeric-curcumin-t1489.html
- Acido Alfa Lipoico: suplementos-vitaminas-f114/acido-alfa-lipoico-ala-t1524.html
- Omega 3: suplementos-vitaminas-f114/pescado-azul-mercurio-t1499.html
- Anatabine: Ver Anatabloc
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Re: Inflamación

Mensajepor Dalamar » 17 Abr 2014 17:30

Sugar Tied to Fatal Heart Woes; Soda’s a Culprit
February 4, 2014
The largest study of its kind in history reveals sugar could potentially play a role in the occurrence of heart attacks. Sugar has been known for some time to increase blood pressure and bad cholesterol in some patients. Now it appears excess sugar could also affect inflammation related to heart disease. The study, from the US Centers for Disease Control and Prevention, looked at data from 1988 through 2010, comprising over 30,000 Americans with an average age of 44.
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Re: Inflamación

Mensajepor Dalamar » 21 May 2014 11:34

Un artículo muy interesante sobre la restricción caloríca y la inflamación:

http://www.juventudybelleza.com/2010/06 ... a.html?m=1
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Re: Inflamación

Mensajepor Dalamar » 06 Ago 2014 20:43

Behind that is sarilumab, a Sanofi-shared rheumatoid arthritis treatment that works by halting the IL-6 receptor to tamp down inflammation. The partners disclosed some strong Phase III results earlier this summer and expect to report results from their 6-study late-stage program next year, targeting regulatory applications after that.


Tendremos que hablar de los receptores y pathways por aqui... es un tema muy interesante! Y de las mutaciones geneticas relacionadas!

Boehringer Ingelheim has handed back the rights to a drug development project targeting pain and inflammation, ending a long-standing partnership with Orexo. The deal, initially struck in 2005, focused on therapies that inhibit the hormone prostaglandin E2, which plays a role in inflammatory processes around the body, according to Orexo.
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Re: Inflamación

Mensajepor Dalamar » 25 Ago 2014 17:49

Tissue Regeneration Using Anti-Inflammatory Nanomolecules

New work appearing in the journal Biomaterials reveals the creation of self-assembling peptide-based nanomaterials, which could aid in tissue repair and help offset or eliminate the inflammatory response that slows healing. In the case of skin grafting, for instance, foreign materials used to help the graft take hold can slow the healing process. This new material, however, shows promise to keep inflammation in check, as early tests of this new material platform in bladder scaffolding tests have shown encouraging results.
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Re: Inflamación

Mensajepor Dalamar » 10 Oct 2014 19:15

Chronic inflammation, dubbed inflammaging by gerontologist Claudio Franceschi, is actually a form of autoimmune disorder. Three scientists won the 2011 Nobel prize in medicine for their work explaining how our innate immune systems, which protect us when we’re young, can shorten our lives.

A major player in this process is the immune system’s alarm, nuclear factor kappa B (NF-kB). When we are young, NF-kB activates an immune response when we are injured or infected, then promptly turns off when it’s no longer needed. For various reasons, NF-kB increasingly activates as we age, apparently interpreting the effects of aging as injury, and never really shuts down. Cytokines and other immune system weapons are turned against us, leading to a wide variety of inflammation-related diseases.
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Re: Inflamación

Mensajepor Dalamar » 25 Oct 2014 19:27

La obesidad es algo muy inflamatorio:

Mid-section fat is the really dangerous fat that produces 17 hormones, 15 of which are inflammatory (triggering obesity, diabetes and heart disease)
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Re: Inflamación

Mensajepor Dalamar » 02 Nov 2014 09:19

Mecanismos por los que la curcuma y el resveratrol previenen la inflamacion (Bloqueando VEGF-A, IL-6 y IL-8): http://ard.bmj.com/content/71/Suppl_1/A90.2

Conclusion Curcumin and resveratrol are natural compounds representing strong anti-inflammatory effects and could play a role in the treatment of chronic inflammatory diseases like RA.
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Re: Inflamación

Mensajepor Dalamar » 09 Sep 2017 19:51

Depression is a physical illness which could be treated with anti-inflammatory drugs, scientists suggest


Mi mejor metodi para reducir la inflamación? El ayuno intermitente...
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